- BrandLibero
Prescription: Yes
Preparations: Tablets: 250, 500, and 750 mg; oral solution: 25 mg/ml; injection: 5 mg/ml and 25 mg/ml.
Storage: Levofloxacin should be stored between 15-30 c (59-86 f)
Prescribed For: Levofloxacin is used to treat infections of the sinuses, skin, lungs, ears, airways, bones, and joints caused by susceptible bacteria. Levofloxacin also is frequently used to treat urinary infections, including those resistant to other antibiotics, as well as prostatitis (infection of the prostate). Levofloxacin is effective in treating infectious diarrhea caused by e. Coli,campylobacter jejuni, and shigella bacteria. Levofloxacin also can be used to treat various obstetric infections, including mastitis (infection of the breast).
Dosing: The usual dose is 250-750 mg given once daily for 5-60 days depending on the type of infection. It is important to take oral formulations at least 2 hours before or 2 hours after any antacid or mineral supplement containing iron, calcium, zinc, or magnesium since these bind levofloxacin and prevent its absorption into the body.
Drug Interactions: Iron, calcium, zinc, or magnesium can attach to levofloxacin and other fluoroquinolones and prevent their absorption from the intestine into the blood. Therefore, products (for example, antacids) that contain iron, calcium, zinc or magnesium should be taken at least 2 hours before or 2 hours after levofloxacin. Other drugs that contain these minerals and can similarly interact with levofloxacin include sucralfate (carafate) and didanosine (videx, videx ec).
Taking nonsteroidal antiinflammatory drugs (nsaids) with levofloxacin may increase the risk of cns stimulation, resulting in over-excitation. There have been reports of changes in blood sugar (increases and decreases) in patients treated with fluoroquinolones and antidiabetic agents. Fluoroquinolones may increase blood levels of theophylline (theodur), cyclosporine (sandimmune, neoral), and the effect of warfarin (coumadin).
Pregnancy: Levofloxacin is not recommended for use in pregnant women since levofloxacin causes joint and bone deformities in juvenile animals of several species.